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The FDA ( Food and Drug Administration ) approved Baraclude ( Entecavir ) tablets and oral solution for the treatment of chronic hepatitis B in adults. Baraclude is indicated for the treatment of ...


Hepatic fibrosis, the common response associated with chronic liver diseases, ultimately leads to cirrhosis. Researchers showed that activation of hepatic cannabinoid CB2 receptors limits progression ...


Measuring liver stiffness using transient elastography can predict severe portal hypertension in patients with hepatitis C-related cirrhosis.As liver disease progresses, fibrosis leads to portal hyper ...


Low-dose oral Interferon could exert immune-modulating effects in human. Researchers have conducted a clinical trial to investigate the efficacy of oral Interferon-alpha in preventing hepatitis C rela ...


Results from RESTORE , a phase III, multicentre, single-arm, open-label study presented at the International Liver Congress 2014 showed that Simeprevir ( Olysio )150 mg once-daily for 12 weeks in comb ...


The first detailed results from pivotal phase III study, PEARL-III, were presented as part of the 21st Conference on Retroviruses and Opportunistic Infections ( CROI ). PEARL-III evaluated the effica ...


Whether long-term suppression of replication of hepatitis B virus ( HBV ) has any beneficial effect on regression of advanced liver fibrosis associated with chronic HBV infection remains unclear. A s ...


All treatment-naïve and –experienced patients with compensated or decompensated chronic liver disease related to ( hepatitis C virus ) HCV, who are willing to be treated and who have no contra-indicat ...


Interim results from one of the ongoing phase II studies of RG-101 for the treatment of hepatitis C virus infection ( HCV ) were announced. The study was designed to evaluate a shortened, 4-week tr ...


Detailed results from an open-label phase 2 trial evaluating the investigational apoptosis signal-regulating kinase 1 ( ASK1 ) inhibitor Selonsertib ( formerly GS-4997 ) alone or in combination with t ...